Detecting Mutations in Tissue and Cells
This research project aims to develop a cutting-edge molecular tool for highly sensitive and specific profiling of genetic mutations in intact tissues and cells. Our tool can enable researchers and clinicians to detect, map, and quantify mutations at the single-cell level within their native spatial context, overcoming current limitations in tissue disaggregation and loss of spatial information.
Our new molecular tool can help significantly advance molecular diagnostics and research, allowing for early detection of disease-related mutations, tracking of tumor heterogeneity, and the discovery of novel biomarkers in complex diseases such as cancer, neurodegeneration, and genetic disorders. This technology holds great promise for personalized medicine by providing deeper insights into the genetic makeup of diseased tissues, aiding in the development of targeted therapies.
We have proof of concept data in the lab and are moving towards clinical research applications for eventual clinical use